
VYSRE Science
What is Neuro Stimulation? tCWS
Neuro-stimulation is a gentle and non-invasive approach to delivering low-intensity electrical current to the surface of the brain. VYSRE's patented transcranial complex waveform stimulation (tCWS) is built on the well-studied and long-standing transcranial electrical stimulation (tES) technology. Within the class of tES, there are three types of stimulation patterns: transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS) and transcranial random noise stimulation (tRNS).
Our system can simultaneously apply any combination of these three stimulation modalities along with more complex stimulation waveforms to different brain parts to create bilateral and cross-lateral stimulation patterns to maximize neuroplasticity.
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The VYSRE device is unique in that it targets select areas of the brain to deliver a combination of tES in concurrent and sequential patterns using our patent-pending design and proprietary software. The device has several node clusters within adjustable bands that allow us to target specific areas of the brain with pinpoint precision and can stimulate separate areas of the brain simultaneously, providing a systematic improvement to the brain’s ability to create, problem-solve and enhance performance.
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How does VYSRE work?
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What are the effects of the different VYBES?
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VYBE 1 activates the dorsolateral prefrontal cortex, orbitofrontal cortex, and other parts of the brain via unique patterns of tES stimulations targeting executive function and cognitive flexibility, which is needed for creative thinking, planning, focusing on tasks, and implementing new projects.
VYBE 1
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VYBE 2 activates the dorsolateral prefrontal cortex using a unique combination of tES stimulations targeting the brain’s ability to pay attention to active tasks and split-second decision-making/reaction time.
VYBE 2
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VYBE 3 activates the frontal cortex, parietal cortex, primary motor cortex, frontal eye field, occipital cortex, and other brain regions to enhance task-oriented skills, stimulation-based activities, repetitive action motions, precision activities, and acquisition and execution functions.
VYBE 3
The tDCS, tACS and tRNS Methods
Transcranial electrical stimulation (tES) technology covers a broad and diverse methodology of implementing varied low-intensity electrical currents to enhance the brain network and influence the neuroplasticity of neuronal pathways. Different from other more powerful brain stimulation technology, tES delivers a very gentle and subthreshold modulatory synaptic impact through transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS) and transcranial random noise stimulation (tRNS).
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Each stimulation method within the tES has significant differences. Looking at tDCS, it is a direct current believed to have effects on high-order cortical processes like decision making, memory, language, sensory perception, pain, attention, cognitive flexibility, planning, simulation-based enhancements, and precision control through a linear patterned waveform. Separately, tACS delivers alternating current in sine-wave patterns believed to be a more precise influence over tDCS to modulate basic motor and sensory processes as well as higher cognitive functions like memory, ambiguous perception and decision making. Adding tRNS, randomized current frequencies and milliamperes stimulation pattern, there are potential enhancements of neural processing and memory, motor activation and motor synchrony.
What is transcranial electrical stimulation (tES)?
The effectiveness of tES, be it tDCS, tACS or tRNS, depends on the application of the different stimulation patterns. Using small, low-intensity electrical currents, tES can stimulate brain tissue through the scalp, influencing brain activity and neuronal activity via “priming” neurons to subthreshold levels for cortical excitability. Unlike more powerful brain stimulation technology, such as repetitive transcranial magnetic stimulation (rTMS) that directly activates neuron action potentials and increases neuronal propagation, tES provides a more comfortable experience that is safe for at-home use.
How does tES work?

How do we know tES works?
In the past decades, countless scientific and clinical studies, peer reviews, and meta-reports support and validate the biological and clinical impact of tES. Using low-intensity electricity to impact the brain and body has been used for around 100 years, and over the years, the use of electricity in medical care has dramatically evolved.
Supported by decades of research, scientific studies and reviews, tDCS stimulation has demonstrated an evidence-based impact on modulating effects on brain task performance and mood improvement. The question is not whether tES works but how we can target the intended performance enhancement and feature we want. The VYSRE device offers a customized solution and tailored brain-stimulation to address the individual's goal using our technology.
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Consumers have been missing a device that can fully maximize and customize the utilization of all the tES patterns. VYSRE is the solution that can bridge decades of studies and data into an elegant and succinct solution for consumers to take advantage of.